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Article

Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor

1 Apr 2017

Abstract excerpt

Background— UK Biobank is the world’s largest repository for phenotypic and genotypic information for individuals of European ancestry. Here, we leverage UK Biobank to understand the inherited basis for venous thromboembolism (VTE), a leading cause of cardiovascular mortality. Methods and Results— We identified 3290 VTE cases and 116 868 controls through billing code–based phenotyping. We performed a genome-wide...

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Share to Blood Coagulation and Thrombosis Mechanisms
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PMID: 28373160
DOI: 10.1161/circgenetics.116.001643

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