Article
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2012
Heit J A, Armasu S M, Asmann Y W, Cunningham J M, Matsumoto M E, Petterson T M, De Andrade M
Abstract excerpt
OBJECTIVES: To identify venous thromboembolism (VTE) disease-susceptibility genes. PATIENTS AND METHODS: We performed in silico genome wide association scan (GWAS) analyses using genotype data imputed to approximately 2.5 million single-nucleotide polymorphisms (SNPs) from adults with objectively-diagnosed VTE (n=1503), and controls frequency matched on age and gender (n=1459; discovery population)....
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