Article
Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism.
Thrombosis and haemostasis - 1 Sept 2021
Herrera-Rivero Marisol, Stoll Monika, Hegenbarth Jana-Charlotte, Rühle Frank, Limperger Verena, Junker Ralf, Franke André, Hoffmann Per, Shneyder Maria, Stach Michael, Nowak-Göttl Ulrike
Abstract excerpt
Previous genome-wide association studies (GWASs) have established several susceptibility genes for venous thromboembolism (VTE) and suggested many others. However, a large proportion of the genetic variance in VTE remains unexplained. Here, we report genome-wide single- and multimarker as well as gene-level associations with VTE in 964 cases and 899 healthy controls of European ancestry. We report 19 loci at the...
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