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Article

Benchmarking predictions of allostery in liver pyruvate kinase in CAGI4.

Human mutation - 1 Sept 2017

Xu Qifang, Tang Qingling, Katsonis Panagiotis, Lichtarge Olivier, Jones David, Bovo Samuele, Babbi Giulia, Martelli Pier L, Casadio Rita, Lee Gyu Rie, Seok Chaok, Fenton Aron W, Dunbrack Roland L

Abstract excerpt

The Critical Assessment of Genome Interpretation (CAGI) is a global community experiment to objectively assess computational methods for predicting phenotypic impacts of genomic variation. One of the 2015-2016 competitions focused on predicting the influence of mutations on the allosteric regulation of human liver pyruvate kinase. More than 30 different researchers accessed the challenge data. However, only four...

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PMID: 28370845
DOI: 10.1002/humu.23222
PMCID: PMC5561472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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