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CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation.

Human mutation - 1 Sept 2019

Katsonis Panagiotis, Lichtarge Olivier

Abstract excerpt

Many computational approaches estimate the effect of coding variants, but their predictions often disagree with each other. These contradictions confound users and raise questions regarding reliability. Performance assessments can indicate the expected accuracy for each method and highlight advantages and limitations. The Critical Assessment of Genome Interpretation (CAGI) community aims to organize objective and...

Topics

Computational Biology
Databases, Genetic
Evolution, Molecular
Genetic Fitness
Genetic Predisposition to Disease
Genetic Variation
Humans
Phenotype
Sequence Alignment
Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31317604
DOI: 10.1002/humu.23873
PMCID: PMC6900054

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