Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 targets TSPAN8 to prevent invasion in melanoma cells

3 Apr 2017

Abstract excerpt

Cutaneous melanoma is a very deadly cancer because of its proclivity to metastasize. Despite the recent development of targeted and immune therapies, patient survival remains low. It is therefore crucial to enhance understanding of the molecular mechanisms underlying invasion. We previously identified tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28368391
DOI: 10.1038/oncsis.2017.11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 targets TSPAN8 to prevent invasion in melanoma cellsPMID 28368391Read ↗

Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells.Semantic proximity Read ↗

Transcriptome Analysis and Single-Cell Sequencing Analysis Constructed the Metastasis-Related Signature in Melanoma and Identified CD74 as a Novel BiomarkerSemantic proximity Read ↗

Altered Expression of Shorter p53 Family Isoforms Can Impact Melanoma AggressivenessSemantic proximity Read ↗

Thrombospondin-1 and cutaneous melanoma.Semantic proximity Read ↗

Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2.Semantic proximity Read ↗

Targeting invasive properties of melanoma cells.Semantic proximity Read ↗

Molecular Regulation and Oncogenic Functions of TSPAN8Semantic proximity Read ↗

Long non-coding RNA MIR4435-2HG recruits miR-802 from FLOT2 to promote melanoma progression.Semantic proximity Read ↗

Thymosin β4 Regulates Focal Adhesion Formation in Human Melanoma Cells and Affects Their Migration and InvasionSemantic proximity Read ↗

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma.Semantic proximity Read ↗

Melanoma invasion – current knowledge and future directionsSemantic proximity Read ↗

p53 Family in Resistance to Targeted Therapy of Melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.