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Molecular Regulation and Oncogenic Functions of TSPAN8

19 Jan 2024

Abstract excerpt

Tetraspanins, a superfamily of small integral membrane proteins, are characterized by four transmembrane domains and conserved protein motifs that are configured into a unique molecular topology and structure in the plasma membrane. They act as key organizers of the plasma membrane, orchestrating the formation of specialized microdomains called “tetraspanin-enriched microdomains (TEMs)” or “tetraspanin...

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PMID: 38275818
DOI: 10.3390/cells13020193

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