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Melanoma invasion – current knowledge and future directions

16 May 2007

Abstract excerpt

The acquisition of invasive behaviour is the key transition in the progression of benign melanocyte hyperplasia to life threatening melanoma. Understanding this transition and the mechanisms of invasion are the key to understanding why malignant melanoma is such a devastating disease and will aid treatment strategies. Underlying the invasive behaviour is increased cell motility caused by changes in cytoskeletal...

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PMID: 17516924
DOI: 10.1111/j.1600-0749.2007.00378.x

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