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Thymosin β4 Regulates Focal Adhesion Formation in Human Melanoma Cells and Affects Their Migration and Invasion

23 Dec 2019

Abstract excerpt

Thymosin β4 (Tβ4), a multifunctional 44-amino acid polypeptide and a member of actin-binding proteins, plays an important role in developmental processes and wound healing. In recent years an increasing number of data has been published suggesting Tβ4’s involvement in tumorigenesis. However, Tβ4’s role in melanoma tumour development still remains to be elucidated. In our study we demonstrate that Tβ4 is crucial...

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PMID: 31921836
DOI: 10.3389/fcell.2019.00304

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