Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myeloid cells expressing high level of CD45 are associated with a distinct activated phenotype in glioma.

Immunologic research - 1 Jun 2017

Brandenburg Susan, Turkowski Kati, Mueller Annett, Radev Yordan T, Seidlitz Sabine, Vajkoczy Peter

Abstract excerpt

Glioblastoma multiforme is characterized by high accumulation of microglia/macrophages. The function of these tumor-infiltrating myeloid cells is not sufficiently elucidated. Therefore, a better understanding of the precise immune cell composition and function in brain tumors is required. In rodent glioma models, two different myeloid cell populations exist, determined by the expression level of CD45, namely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Antigens, Ly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD11b Antigen

Share to Interleukin-10

Share to Leukocyte Common Antigens

Share to Macrophage Activation

Share to Microglia

Share to Myeloid-Derived Suppressor Cells

Source

Identifiers

PMID: 28367602
DOI: 10.1007/s12026-017-8915-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myeloid cells expressing high level of CD45 are associated with a distinct activated phenotype in glioma.PMID 28367602Read ↗

Phenotypic plasticity of myeloid cells in glioblastoma development, progression, and therapeutics.Semantic proximity Read ↗

The Eclectic Nature of Glioma-Infiltrating Macrophages and Microglia.Semantic proximity Read ↗

Glioma-associated macrophages: unraveling their dual role in the microenvironment and therapeutic implicationsSemantic proximity Read ↗

Microglia-glioma cross-talk: a two way approach to new strategies against glioma.Semantic proximity Read ↗

Increased Microglia/Macrophage Gene Expression in a Subset of Adult and Pediatric AstrocytomasSemantic proximity Read ↗

Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1Semantic proximity Read ↗

Tumor-specific neutrophils originating from meninges promote glioblastomaSemantic proximity Read ↗

Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2 <sup>+</sup> myeloid cells into the tumor microenvironment in a redundant mannerSemantic proximity Read ↗

In vitro generated macrophages reflect the immunosuppressive phenotype of in vivo glioblastoma-associated macrophages.Semantic proximity Read ↗

CSF1 Overexpression Promotes High-Grade Glioma Formation without Impacting the Polarization Status of Glioma-Associated Microglia and MacrophagesSemantic proximity Read ↗

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in GlioblastomaSemantic proximity Read ↗

CD206 Expression in Induced Microglia-Like Cells From Peripheral Blood as a Surrogate Biomarker for the Specific Immune Microenvironment of Neurosurgical Diseases Including Glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.