Article
CD206 Expression in Induced Microglia-Like Cells From Peripheral Blood as a Surrogate Biomarker for the Specific Immune Microenvironment of Neurosurgical Diseases Including Glioma.
Frontiers in immunology - 1 Jan 2021
Tanaka Shunya, Ohgidani Masahiro, Hata Nobuhiro, Inamine Shogo, Sagata Noriaki, Shirouzu Noritoshi, Mukae Nobutaka, Suzuki Satoshi O, Hamasaki Hideomi, Hatae Ryusuke, Sangatsuda Yuhei, Fujioka Yutaka, Takigawa Kosuke, Funakoshi Yusuke, Iwaki Toru, Hosoi Masako, Iihara Koji, Mizoguchi Masahiro, Kato Takahiro A
Abstract excerpt
Targeting the unique glioma immune microenvironment is a promising approach in developing breakthrough immunotherapy treatments. However, recent advances in immunotherapy, including the development of immune checkpoint inhibitors, have not improved the outcomes of patients with glioma. A way of monitoring biological activity of immune cells in neural tissues affected by glioma should be developed to address this...
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