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Article

Increased Microglia/Macrophage Gene Expression in a Subset of Adult and Pediatric Astrocytomas

22 Aug 2012

Abstract excerpt

Glioblastoma (GBM) is a highly malignant brain tumor with a dismal prognosis. Gene expression profiling of GBM has revealed clinically relevant tumor subtypes, and this provides exciting opportunities to better understand disease pathogenesis. Results from an increasing number of studies demonstrate a role for the immune response in cancer progression, yet it is unclear how the immune response differs across...

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PMID: 22937035
DOI: 10.1371/journal.pone.0043339

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