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Article

G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Sept 2017

Luo Chi-Wen, Wang Jaw-Yuan, Hung Wen-Chun, Peng Guang, Tsai Ya-Li, Chang Tsung-Ming, Chai Chee-Yin, Lin Chih-Hung, Pan Mei-Ren

Abstract excerpt

BACKGROUND AND PURPOSE: Neoadjuvant concurrent chemoradiotherapy (CCRT) is a standard treatment of locally advanced colon cancer cell (CRC). In order to maximize efficacy and minimize toxicity, new drugs have been developed and used in combination with CCRT. Recently, it has been shown that G9a plays a role in mediating phenotypes of cancer stem cells (CSCs). This study aimed to characterize G9a as a biomarker in...

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PMID: 28351524
DOI: 10.1016/j.radonc.2017.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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