Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Formation of Polyploid Giant Cancer Cells Involves in the Prognostic Value of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer

29 Aug 2019

Abstract excerpt

We previously reported that polyploid giant cancer cells (PGCCs) exhibit cancer stem cell properties and can generate daughter cells with the epithelial-mesenchymal transition phenotype. This study investigated the role of PGCC formation in the prognostic value of neoadjuvant chemoradiation therapy (nCRT) in locally advanced rectal cancer (LARC). The morphological characteristics were observed in patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Surgical Treatments
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31558902
DOI: 10.1155/2019/2316436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Formation of Polyploid Giant Cancer Cells Involves in the Prognostic Value of Neoadjuvant Chemoradiation in Locally Advanced Rectal CancerPMID 31558902Read ↗

Dormant cancer cells and polyploid giant cancer cells: The roots of cancer recurrence and metastasisSemantic proximity Read ↗

Understanding Polyploid Giant Cancer Cells: From Molecular Mechanisms to Clinical ImplicationsSemantic proximity Read ↗

Molecular mechanism of vimentin nuclear localization associated with the migration and invasion of daughter cells derived from polyploid giant cancer cellsSemantic proximity Read ↗

Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer TreatmentSemantic proximity Read ↗

Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosisSemantic proximity Read ↗

Senescence in polyploid giant cancer cells: A road that leads to chemoresistance.Semantic proximity Read ↗

Human cell polyploidization: The good and the evilSemantic proximity Read ↗

Polyploid Giant Cancer Cells (PGCCs): The Evil Roots of CancerSemantic proximity Read ↗

Tumor stroma and differentiated cancer cells can be originated directly from polyploid giant cancer cells induced by paclitaxelSemantic proximity Read ↗

Polyploid giant cancer cells and cancer progressionSemantic proximity Read ↗

G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response.Semantic proximity Read ↗

The life cycle of polyploid giant cancer cells and dormancy in cancer: Opportunities for novel therapeutic interventionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.