Article
Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs
1 Jun 2013
Abstract excerpt
AIM: Cancer stem cells have the capacity to initiate and sustain tumor growth. In this study, we established a CD44(+) colorectal cancer stem cell line with particular emphasis on its self-renewal capacity, enhanced tumor initiation and drug resistance. METHODS: Fresh colon cancer and paired normal colon tissues were collected from 13 patients who had not received chemotherapy or radiotherapy prior to surgery....
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