Back to search

Article

Radiochemotherapy-induced DNA repair promotes the biogenesis of gastric cancer stem cells

2022-05-09

Abstract excerpt

<h4>Background: </h4> Clinically, metastasis and recurrence occurred after routine radio-chemotherapy in dozens of cases of gastric cancer, mainly attributed to the role of cancer stem cells (CSCs). Actually, radio-chemotherapy could induce DNA damages, leading to activation of DNA repair which might be associated with acquisition of stem cell phenotype. Hitherto, the contribution made by active DNA repair to stem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
55ccb918-3c9c-569e-a331-ca06a18b4d8a
DOI
10.21203/rs.3.rs-1384850/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Radiochemotherapy-induced DNA repair promotes the biogenesis of gastric cancer stem cellsDOI 10.21203/rs.3.rs-1384850/v1
Radiochemotherapy-induced DNA repair promotes the biogenesis of gastric cancer stem cellsSemantic proximity
Targeting Gastric Cancer Stem Cells to Enhance Treatment ResponseSemantic proximity
Identification of stem cell-related subtypes and risk scoring for gastric cancer based on stem genomic profilingSemantic proximity
Comprehensive analysis of transcriptome data stemness indices identifies key genes for controlling cancer stem cell characteristics in gastric cancerSemantic proximity
Cancer stem cells in human digestive tract malignancies.Semantic proximity
circFAM73A&nbsp;Promotes Cancer Stem Cell-like Properties of Gastric Cancer Through miR-490-3p/HMGA2&nbsp;Positive Feedback and HNRNPK-mediated β-catenin Stabilization.Semantic proximity
Identification of Key Genes for Controlling Cancer Stem Cell Characteristics in Gastric CancerSemantic proximity
Gastric cancer derived mesenchymal stem cells promoted DNA repair and cisplatin resistance through up-regulating PD-L1/Rad51 in gastric cancerSemantic proximity
Identification of cancer stem cell-related biomarkers in intestinal-type and diffuse-type gastric cancer by stemness index and weighted correlation network analysisSemantic proximity
Requirement of transcription factor NME2 for the maintenance of the stemness of gastric cancer stem-like cellsSemantic proximity
Proliferative and quiescent human gastric cancer stem-like cells are associated with differential chemoresistance and patient mortalitySemantic proximity
Cancer stem cells in human gastrointestinal cancerSemantic proximity
Select a neighboring publication to make it the new centre.