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Article

Characterization of the B Cell Receptor Repertoire in the Intestinal Mucosa and of Tumor-Infiltrating Lymphocytes in Colorectal Adenoma and Carcinoma.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2017

Zhang Wei, Feng Qiang, Wang Changxi, Zeng Xiaojing, Du Yuanping, Lin Liya, Wu Jinghua, Fu Longfei, Yang Kai, Xu Xiaoying, Xu Hanshi, Zhao Yi, Li Xuemei, Schoenauer Ursula Huber, Stadlmayr Andreas, Saksena Nitin K, Tilg Herbert, Datz Christian, Liu Xiao

Abstract excerpt

The B cells inhabited in mucosa play a vital role in mediating homeostasis with autoantigens and external Ags. Tumor-infiltrating lymphocytes are potential prognostic markers and therapeutic agents for cancer. However, the spatial heterogeneity of the B cell repertoire in intestinal mucosa and the tumor-infiltrating lymphocytes in colorectal cancer (CRC) remain poorly understood. In this study, we developed an...

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PMID: 28348270
DOI: 10.4049/jimmunol.1602039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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