Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human colorectal cancer cells frequently express IgG and display unique Ig repertoire

15 Mar 2019

Abstract excerpt

BACKGROUND: There is growing evidence proving that many human carcinomas, including colon cancer, can overexpress immunoglobulin (Ig); the non B cancer cell-derived Ig usually displayed unique V(D)J rearrangement pattern that are distinct from B cell-derived Ig. Especially, the cancer-derived Ig plays important roles in cancer initiation, progression, and metastasis. However, it still remains unclear if the colon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mast cells and histamine
Share to Monoclonal and Polyclonal Antibodies Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30918593
DOI: 10.4251/wjgo.v11.i3.195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human colorectal cancer cells frequently express IgG and display unique Ig repertoirePMID 30918593Read ↗

A germline variant of human IgG1+ B cell receptor represses colorectal tumorigenesis and progression by shaping the tumor microenvironmentSemantic proximity Read ↗

Characterization of the B Cell Receptor Repertoire in the Intestinal Mucosa and of Tumor-Infiltrating Lymphocytes in Colorectal Adenoma and Carcinoma.Semantic proximity Read ↗

Immunoglobulin Expression in Cancer Cells and Its Critical Roles in TumorigenesisSemantic proximity Read ↗

Immunogenetic Profiling for Gastric Cancers Identifies Sulfated Glycosaminoglycans as Major and Functional B Cell Antigens in Human MalignanciesSemantic proximity Read ↗

The v8-10 variant isoform of CD44 is selectively expressed in the normal human colonic stem cell niche and frequently is overexpressed in colon carcinomas during tumor developmentSemantic proximity Read ↗

Immunoglobulin Gene Transcripts Have Distinct VHDJH Recombination Characteristics in Human Epithelial Cancer CellsSemantic proximity Read ↗

Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patientsSemantic proximity Read ↗

Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomasSemantic proximity Read ↗

Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.Semantic proximity Read ↗

The antibody repertoire of colorectal cancerSemantic proximity Read ↗

IgA and IgM V(H) repertoires in human colon: evidence for clonally expanded B cells that are widely disseminated.Semantic proximity Read ↗

CANCEROUS IMMUNOGLOBULINS AND CA215: IMPLICATIONS IN CANCER IMMUNOLOGYSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.