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Article

Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.

Blood - 24 Dec 2015

Zhou Yuhang, Abraham Shaji, Andre Pierrette, Edelstein Leonard C, Shaw Chad A, Dangelmaier Carol A, Tsygankov Alexander Y, Kunapuli Satya P, Bray Paul F, McKenzie Steven E

Abstract excerpt

Fc receptor for IgG IIA (FcγRIIA)-mediated platelet activation is essential in heparin-induced thrombocytopenia (HIT) and other immune-mediated thrombocytopenia and thrombosis disorders. There is considerable interindividual variation in platelet FcγRIIA activation, the reasons for which remain unclear. We hypothesized that genetic variations between FcγRIIA hyper- and hyporesponders regulate FcγRIIA-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26516227
DOI: 10.1182/blood-2015-02-631135
PMCID: PMC4692146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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