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Article

Association between a genome-wide association study-identified locus and the risk of lung cancer in Japanese population.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2012

Ito Hidemi, McKay James D, Hosono Satoyo, Hida Toyoaki, Yatabe Yasushi, Mitsudomi Tetsuya, Brennan Paul, Tanaka Hideo, Matsuo Keitaro

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified 15q25 and 5p15 as lung cancer risk chromosomal regions in whites. The genetic structures of these loci differ between Asians and whites, however, indicating the need for additional studies in Asian populations. To examine the impact of 15p25 and 5p15 on lung cancer risk and smoking intensity, we conducted a case-control study in Japanese population. We...

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PMID: 22430809
DOI: 10.1097/JTO.0b013e3182475028

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