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Article

Genetic regulation of gene expression in the epileptic human hippocampus.

Human molecular genetics - 1 May 2017

Mirza Nasir, Appleton Richard, Burn Sasha, du Plessis Daniel, Duncan Roderick, Farah Jibril Osman, Feenstra Bjarke, Hviid Anders, Josan Vivek, Mohanraj Rajiv, Shukralla Arif, Sills Graeme J, Marson Anthony G, Pirmohamed Munir

Abstract excerpt

Epilepsy is a serious and common neurological disorder. Expression quantitative loci (eQTL) analysis is a vital aid for the identification and interpretation of disease-risk loci. Many eQTLs operate in a tissue- and condition-specific manner. We have performed the first genome-wide cis-eQTL analysis of human hippocampal tissue to include not only normal (n = 22) but also epileptic (n = 22) samples. We demonstrate...

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Identifiers

PMID: 28334860
DOI: 10.1093/hmg/ddx061
PMCID: PMC5411756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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