Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy

10 Mar 2019

Abstract excerpt

Mesial temporal lobe epilepsy with hippocampal sclerosis represents the most common epilepsy syndrome in adult patients with medically intractable partial epilepsy. Mesial temporal lobe epilepsy is usually regarded as a polygenic and complex disorder, still poorly understood but probably caused and perpetuated by dysregulation of numerous biological networks and cellular functions. The study of gene expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epilepsy research and treatment
Share to Genetics and Neurodevelopmental Disorders
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30932156
DOI: 10.1093/brain/awz074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsyPMID 30932156Read ↗

Genetic regulation of gene expression in the epileptic human hippocampus.Semantic proximity Read ↗

Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosisSemantic proximity Read ↗

RNA-seq analysis of hippocampal tissues reveals novel candidate genes for drug refractory epilepsy in patients with MTLE-HSSemantic proximity Read ↗

Pharmacogenomic Analysis of Medial Temporal Lobe Epilepsy with Hippocampal Sclerosis in Humans and Animal ModelsSemantic proximity Read ↗

Identification of gene regulatory networks affected across drug-resistant epilepsiesSemantic proximity Read ↗

Identification of dysregulated transcription factor activity in temporal lobe epilepsySemantic proximity Read ↗

Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A.Semantic proximity Read ↗

Gene expression, genetics, and genomics in epilepsy: some answers, more questions.Semantic proximity Read ↗

Transcriptome analysis reveals higher levels of mobile element-associated abnormal gene transcripts in temporal lobe epilepsy patientsSemantic proximity Read ↗

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte-mediated etiology of epileptic cortical thinning.Semantic proximity Read ↗

The Epigenetics of Epilepsy and Its ProgressionSemantic proximity Read ↗

Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.