Article
MicroRNA-206 regulates vascular smooth muscle cell phenotypic switch and vascular neointimal formation.
Cell biology international - 1 Jul 2017
Sun Huiyan, Cai Songzhi, Zhang Mei, Zhao Juan, Wei Shuping, Luo Yuyu, Meng Xiangyan, Zhou Xin, Li Yuming, Zhang Wencheng
Abstract excerpt
MiR-206 has been found to play a critical role in skeletal muscle proliferation, differentiation, and regeneration. However, little is known about the function of miR-206 in vascular smooth muscle cells (VSMCs) biology. In this study, we will investigate its roles in phenotypic switching of VSMCs and neointimal lesion formation. First, we identified the expression of miR-206 in VSMCs treated with various...
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