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Article

miR-146a-5p mediates atherogenic signalling from immune to vascular cells.

Cardiovascular research - 5 Jun 2026

Climent Montserrat, Zani Stefania, Salvarani Nicolò, Cremonesi Marco, Serio Simone, Sbalchiero Anna, Tramontano Alfonso, Lambroia Luca, Mallia Alice, Civilini Efrem, Banfi Cristina, Elia Leonardo

Abstract excerpt

AIMS: MicroRNAs (miRNAs) regulate gene expression and are involved in various biological processes, including vascular homeostasis. Macrophages (Mϕs) and vascular smooth muscle cells (VSMCs) play key roles in vascular health and disease. However, the communication between Mϕs and VSMCs via miRNAs is not well understood. This study explores the transfer of miR-146a-5p from Mϕs to VSMCs and its role in...

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PMID: 41974110
DOI: 10.1093/cvr/cvag075
PMCID: PMC13241058

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