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Article

A proteasome inhibitor produced by Burkholderia pseudomallei modulates intracellular growth.

Microbial pathogenesis - 1 Jun 2017

Wagley Sariqa, Vanaporn Muthita, Rinchai Darawan, Conejero Laura, Lertmemongkolchai Ganjana, Bancroft Gregory J, Titball Richard W

Abstract excerpt

The NRPS/PKS cluster encodes the enzymes necessary for glidobactin synthesis it is partially conserved in various members of the Burkholderia genus including B. pseudomallei. In this study we have shown that the insertional inactivation or deletion of glbC in this cluster in B. pseudomallei could reduce the ability of the bacterium to survive or grow in murine macrophages or in human neutrophils. Exogenously...

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Identifiers

PMID: 28323151
DOI: 10.1016/j.micpath.2017.03.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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