Article
Molecular characterization of putative virulence determinants in Burkholderia pseudomallei.
TheScientificWorldJournal - 1 Jan 2014
Puah Suat Moi, Puthucheary S D, Wang Jin Town, Pan Yi Jiun, Chua Kek Heng
Abstract excerpt
The Gram-negative saprophyte Burkholderia pseudomallei is the causative agent of melioidosis, an infectious disease which is endemic in Southeast Asia and northern Australia. This bacterium possesses many virulence factors which are thought to contribute to its survival and pathogenicity. Using a virulent clinical isolate of B. pseudomallei and an attenuated strain of the same B. pseudomallei isolate, 6 genes...
Topics
- Animals
- Burkholderia pseudomallei
- Caenorhabditis elegans
- Genes, Bacterial
- Microbial Viability
- Mutagenesis, Insertional
- Mutation
- Virulence
- Virulence Factors
