Article
The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity.
Journal of the American Chemical Society - 2 Jul 2014
Biggins John B, Kang Hahk-Soo, Ternei Melinda A, DeShazer David, Brady Sean F
Abstract excerpt
Increasing evidence has shown that small-molecule chemistry in microbes (i.e., secondary metabolism) can modulate the microbe-host response in infection and pathogenicity. The bacterial disease melioidosis is conferred by the highly virulent, antibiotic-resistant pathogen Burkholderia pseudomallei (BP). Whereas some macromolecular structures have been shown to influence BP virulence (e.g., secretion systems,...
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