Article
Role of quorum sensing in the pathogenicity of Burkholderia pseudomallei.
Journal of medical microbiology - 1 Nov 2004
Ulrich Ricky L, DeShazer David, Brueggemann Ernst E, Hines Harry B, Oyston Petra C, Jeddeloh Jeffrey A
Abstract excerpt
Burkholderia pseudomallei is the causative agent of human and animal melioidosis. The role of quorum sensing (QS) in the in vivo pathogenicity of B. pseudomallei via inhalational exposure of BALB/c mice and intraperitoneal challenge of Syrian hamsters has not been reported. This investigation demonstrates that B. pseudomallei encodes a minimum of three luxI and five luxR homologues that are involved in animal...
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