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Article

A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 May 2017

Blasi Francesco, Bruckmann Chiara, Penkov Dmitry, Dardaei Leila

Abstract excerpt

We report the latest structural information on PREP1 tumor suppressor, the specific "oncogene" and "tumor suppressive" signatures of MEIS1 and PREP1, the molecular rules regulating PREP1 and MEIS1 binding to DNA, and how these can change depending on the interaction with PBX1, cell-type, neoplastic transformation, and intracellular concentration. As both PREP1 and MEIS1 interact with PBX1 they functionally...

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Source

Identifiers

PMID: 28322463
DOI: 10.1002/bies.201600245

Genes

MEIS1
PBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer.PMID 28322463Read ↗

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