Article
Characterization of zebrafish Pax1b and Pax9 in fin bud development.
BioMed research international - 1 Jan 2014
Chen Xuemei, Huang Huizhe, Wang Hua, Guo Fengjin, Du Xiaogang, Ma Linqiang, Zhao Liang, Pan Zhuma, Gui Haibo, Yuan Taixian, Liu Xin, Song Lin, Wang Yiquan, He Junling, Lei Han, Gao Rui
Abstract excerpt
Both Pax1 and Pax9 belong to the important paired box gene family (PAX), which mainly participates in animal development and sclerotome differentiation. To date, the precise molecular mechanism and related signaling pathway of Pax1 remain unclear. In our study, microinjection of morpholino- (MO-) modified antisense oligonucleotides against pax1b induced pectoral fin bud defects. Furthermore, we demonstrate that...
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