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Sequence and expression of the zebrafish alpha‐actinin gene family reveals conservation and diversification among vertebrates

19 Oct 2009

Abstract excerpt

Alpha-actinins are actin microfilament crosslinking proteins. Vertebrate actinins fall into two classes: the broadly-expressed actinins 1 and 4 (actn1 and actn4) and muscle-specific actinins, actn2 and actn3. Members of this family have numerous roles, including regulation of cell adhesion, cell differentiation, directed cell motility, intracellular signaling, and stabilization of f-actin at the sarcomeric Z-line...

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PMID: 19842183
DOI: 10.1002/dvdy.22123

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