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Modeling Inherited Cardiac Disorders

1 Jan 2014

Abstract excerpt

Advances in the understanding and treatment of cardiac disorders have been thwarted by the inability to study beating human cardiac cells in vitro. Induced pluripotent stem cells (iPSCs) bypass this hurdle by enabling the creation of patient-specific iPSC-derived cardiomyocytes (iPSC-CMs). These cells provide a unique platform to study cardiac diseases in vitro, especially hereditary cardiac conditions. To date,...

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PMID: 24632794
DOI: 10.1253/circj.cj-14-0182

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