Article
Polymorphisms of insulin receptor substrate 2 are putative biomarkers for pediatric medulloblastoma: considering the genetic susceptibility and pathological diagnoses.
Nagoya journal of medical science - 1 Feb 2017
Baocheng Wang, Zhao Yang, Meng Wei, Han Yipeng, Wang Jiajia, Liu Feili, Qin Shengying, Ma Jie
Abstract excerpt
Molecular profiling subgrouped medulloblastoma (MB) into four subtypes featured by distinct footprints. However, germline studies on genetic susceptibility in Chinese population have not been reported. To investigate the correlation of polymorphisms involved in the AKT signaling pathway with clinicopathological parameters in pediatric MB, and their contribution to the clinical outcome, we performed a...
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