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Article

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability.

Journal of virology - 15 May 2017

Scott Katherine A, Kotecha Abhay, Seago Julian, Ren Jingshan, Fry Elizabeth E, Stuart David I, Charleston Bryan, Maree Francois F

Abstract excerpt

Foot-and-mouth disease virus (FMDV), particularly strains of the O and SAT serotypes, is notoriously unstable. Consequently, vaccines derived from heat-labile SAT viruses have been linked to the induction of immunity with a poor duration and hence require more frequent vaccinations to ensure protection. In silico calculations predicted residue substitutions that would increase interactions at the interpentamer...

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Source

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Identifiers

PMID: 28298597
DOI: 10.1128/JVI.02312-16
PMCID: PMC5411616

Genes

SAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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