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Article

A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.

Journal of virology - 26 Jul 2021

Dong Hu, Lu Yuanlu, Zhang Yun, Mu Suyu, Wang Nan, Du Ping, Zhi Xiaoying, Wen Xiaobo, Wang Xiangxi, Sun Shiqi, Zhang Yanming, Guo Huichen

Abstract excerpt

Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals that causes a significant economic burden globally. Vaccination is the most effective FMD control strategy. However, FMD virus (FMDV) particles are prone to dissociate when appropriate physical or chemical conditions are unavailable, such as an incomplete cold chain. Such degraded vaccines result in compromised herd...

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Identifiers

PMID: 34011545
DOI: 10.1128/JVI.00177-21
PMCID: PMC8312871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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