Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomics of Hairy Cell Leukemia

23 Feb 2017

Abstract excerpt

Hairy cell leukemia (HCL) is a chronic mature B-cell neoplasm with unique clinicopathologic features and an initial exquisite sensitivity to chemotherapy with purine analogs; however, the disease relapses, often repeatedly. The enigmatic pathogenesis of HCL was recently clarified by the discovery of its underlying genetic cause, the BRAF-V600E kinase-activating mutation, which is somatically and clonally present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Chronic Lymphocytic Leukemia Research
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28297625
DOI: 10.1200/jco.2016.71.1556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomics of Hairy Cell LeukemiaPMID 28297625Read ↗

BRAF V600E mutation in hairy cell leukemia: from bench to bedsideSemantic proximity Read ↗

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activitySemantic proximity Read ↗

BRAF mutations in hairy-cell leukemia.Semantic proximity Read ↗

The Biology of Classic Hairy Cell Leukemia.Semantic proximity Read ↗

[Molecular and therapeutic advances in Hairy cell leukemia].Semantic proximity Read ↗

Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.Semantic proximity Read ↗

Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations.Semantic proximity Read ↗

Hairy Cell Leukaemia.Semantic proximity Read ↗

Historical overview of hairy cell leukemia.Semantic proximity Read ↗

Hairy cell leukemia: Past, present and future.Semantic proximity Read ↗

Hairy cell leukemia: update and current therapeutic approach.Semantic proximity Read ↗

Hairy cell leukemia (HCL) and HCL-like disorders: present, emergent treatment options and future directions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.