Article
Hairy cell leukemia: Past, present and future.
Best practice & research. Clinical haematology - 1 Dec 2015
Getta Bartlomiej M, Park Jae H, Tallman Martin S
Abstract excerpt
This brief review highlights the sequence of therapeutic milestones and advances in our understanding of the biology of hairy cell leukemia (HCL) with a focus on recent molecular findings and how these may be applied to improve disease outcomes in the future. Targeted therapy is discussed in the context of the recently identified BRAF mutation and other genetic findings.
Topics
- Antineoplastic Agents
- B-Lymphocytes
- Cladribine
- Disease Management
- History, 20th Century
- History, 21st Century
- Humans
- Immunotoxins
- Indoles
- Leukemia, Hairy Cell
- Mutation
- Pentostatin