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Article

Historical overview of hairy cell leukemia.

Best practice & research. Clinical haematology - 1 Dec 2015

Andritsos Leslie A, Grever Michael R

Abstract excerpt

Since its discovery in 1923 and further characterization in 1958, hairy cell leukemia (HCL) has undergone enormous advances in the understanding of the biology and treatment of the disease. Initially a uniformly fatal disease, new therapies in rapid succession transformed HCL into a chronic disease with a normal life expectancy in many cases. More recently, the identification of BRAFV600E mutations in the...

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Identifiers

PMID: 26614894
DOI: 10.1016/j.beha.2015.10.018

Genes

BRAF
BTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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