Article
The Biology of Classic Hairy Cell Leukemia.
International journal of molecular sciences - 21 Jul 2021
Bohn Jan-Paul, Salcher Stefan, Pircher Andreas, Untergasser Gerold, Wolf Dominik
Abstract excerpt
Classic hairy cell leukemia (HCL) is a rare mature B-cell malignancy associated with pancytopenia and infectious complications due to progressive infiltration of the bone marrow and spleen. Despite tremendous therapeutic advances achieved with the implementation of purine analogues such as cladribine into clinical practice, the culprit biologic alterations driving this fascinating hematologic disease have long...
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