Article
Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group.
Genes, chromosomes & cancer - 1 Jul 2017
Marcotte Erin L, Pankratz Nathan, Amatruda James F, Frazier A Lindsay, Krailo Mark, Davies Stella, Starr Jacqueline R, Lau Ching C, Roesler Michelle, Langer Erica, Hallstrom Caroline, Hooten Anthony J, Poynter Jenny N
Abstract excerpt
Germ cell tumors (GCT) are a rare form of childhood cancer that originate from the primordial germ cell. Recent genome-wide association studies (GWAS) have identified susceptibility alleles for adult testicular GCT (TGCT). We test whether these SNPs are associated with GCT in pediatric and adolescent populations. This case-parent triad study includes individuals with GCT diagnosed between ages 0 and 19. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.