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Article

Familial testicular germ cell tumours.

Best practice & research. Clinical endocrinology & metabolism - 1 Jun 2010

Kratz Christian P, Mai Phuong L, Greene Mark H

Abstract excerpt

This article defines familial testicular germ cell tumours (FTGCTs) as testicular germ cell tumours (TGCTs) diagnosed in at least two blood relatives, a situation which occurs in 1-2% of all cases of TGCT. Brothers and fathers of TGCT patients have an 8-10- and 4-6-fold increased risk of TGCT, respectively, and an even higher elevated risk of TGCT in twin brothers of men with TGCT has been observed, suggesting...

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Source

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Identifiers

PMID: 20833340
DOI: 10.1016/j.beem.2010.01.005
PMCID: PMC2939736

Genes

BAK1
KITLG
SPRY4

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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