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Article

Associations between variants in KITLG, SPRY4, BAK1, and DMRT1 and pediatric germ cell tumors.

Genes, chromosomes & cancer - 1 Mar 2012

Poynter Jenny N, Hooten Anthony J, Frazier A Lindsay, Ross Julie A

Abstract excerpt

Recent genome wide association studies have identified susceptibility loci for adult testicular germ cell tumors (GCT) near KITLG, SPRY4, BAK1, and DMRT1. We evaluated variants in these four genes to determine whether these are also susceptibility loci for pediatric GCTs. DNA was isolated from 52 pediatric GCTs (ages 0-21 years) obtained from the Cooperative Human Tissue Network. Control DNA was isolated from...

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Source

Identifiers

PMID: 22072546
DOI: 10.1002/gcc.20951

Genes

BAK1
KITLG
SPRY4
DMRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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