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Pediatric Germ Cell Tumors: A Developmental Perspective

1 Jan 2018

Abstract excerpt

Germ cell tumors (GCTs) arising in infants, children, and adolescents present a set of special challenges. GCTs make up about 3% of malignancies in children aged 0-18 and nearly 15% of cancers in adolescents. Epidemiologic and molecular evidence suggests that GCTs in young children likely represent a distinct biologic group as compared to GCTs of older adolescents and adults. Despite this difference, pediatric...

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PMID: 29515628
DOI: 10.1155/2018/9059382

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