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Article

Functional evaluation of genetic variants associated with endometriosis near GREB1.

Human reproduction (Oxford, England) - 1 May 2015

Fung Jenny N, Holdsworth-Carson Sarah J, Sapkota Yadav, Zhao Zhen Zhen, Jones Lincoln, Girling Jane E, Paiva Premila, Healey Martin, Nyholt Dale R, Rogers Peter A W, Montgomery Grant W

Abstract excerpt

STUDY QUESTION: Do DNA variants in the growth regulation by estrogen in breast cancer 1 (GREB1) region regulate endometrial GREB1 expression and increase the risk of developing endometriosis in women? SUMMARY ANSWER: We identified new single nucleotide polymorphisms (SNPs) with strong association with endometriosis at the GREB1 locus although we did not detect altered GREB1 expression in endometriosis patients...

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Source

Identifiers

PMID: 25788566
DOI: 10.1093/humrep/dev051

Genes

GREB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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