Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex-Dependent Effects of HO-1 Deletion from Adipocytes in Mice.

International journal of molecular sciences - 11 Mar 2017

Hosick Peter A, Weeks Mary Frances, Hankins Michael W, Moore Kyle H, Stec David E

Abstract excerpt

Induction of heme oxygenase-1 (HO-1) has been demonstrated to decrease body weight and improve insulin sensitivity in several models of obesity in rodents. To further study the role of HO-1 in adipose tissue, we created an adipose-specific HO-1 knockout mouse model. Male and female mice were fed either a control or a high-fat diet for 30 weeks. Body weights were measured weekly and body composition, fasting blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Adiponectin
Share to Body Composition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, High-Fat

Share to Fasting

Share to Heme Oxygenase-1

Share to Hyperinsulinism

Share to Inflammation Mediators

Source

Open in PubMed Open full text

Identifiers

PMID: 28287466
DOI: 10.3390/ijms18030611
PMCID: PMC5372627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Sex-Dependent Effects of HO-1 Deletion from Adipocytes in Mice.PMID 28287466Read ↗

Ablation of adipose-HO-1 expression increases white fat over beige fat through inhibition of mitochondrial fusion and of PGC1α in female mice.Semantic proximity Read ↗

Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity.Semantic proximity Read ↗

Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice.Semantic proximity Read ↗

Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient miceSemantic proximity Read ↗

Sex-Specific Peripheral Metabolic and Central Hypothalamic Responses in a CD1 Mouse Model of Diet-Induced ObesitySemantic proximity Read ↗

WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism.Semantic proximity Read ↗

Sex Disparities in Obesity: A Comprehensive Review of Hormonal and Genetic Influences on Obesity-Related Phenotypes.Semantic proximity Read ↗

Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restrictionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.