Article

Sex-Specific Peripheral Metabolic and Central Hypothalamic Responses in a CD1 Mouse Model of Diet-Induced Obesity

2026-08-03

Abstract excerpt

<title>Abstract</title> <p>Obesity, a chronic condition influenced by ultra-processed foods, has emerged as a global health crisis. To encompass human genetic diversity and metabolic sex differences, this research assessed peripheral and central metabolic responses to a high-fat, high-sucrose diet (HF-HSD) in outbred CD1 mice of both sexes. Male and female mice were fed either a standard diet or an HF-HSD (44% fa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cc489bdd-296e-571c-b7f8-7746cb80e4a7
DOI: 10.21203/rs.3.rs-10416261/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex-Specific Peripheral Metabolic and Central Hypothalamic Responses in a CD1 Mouse Model of Diet-Induced ObesityDOI 10.21203/rs.3.rs-10416261/v1Read

Integrated Ultrasound Characterization of the Diet-Induced Obesity (Dio) Model in Young Adult C57bl/6j Mice: Assessment of Cardiovascular, Renal and Hepatic ChangesSemantic proximity Read

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in miceSemantic proximity Read

Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J miceSemantic proximity Read

The Impact of a Western Diet with High Salt on Metabolic Outcomes in Male C57bl/6J MiceSemantic proximity Read

Humanized diet and thermoneutral housing enable sex-aware dissection of the MASLD-T2D-CVD triadSemantic proximity Read

Genetic background and sex control the outcome of high-fat diet feeding in miceSemantic proximity Read

The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N mice.Semantic proximity Read

Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthoodSemantic proximity Read

A systematic analysis of rodent models implicates adipogenesis and innate immunity in pathogenesis of fatty liver diseaseSemantic proximity Read

Differences in metabolic and liver pathobiology induced by two dietary mouse models of nonalcoholic fatty liver diseaseSemantic proximity Read

High Fat Rodent Models of Type 2 Diabetes: From Rodent to HumanSemantic proximity Read

Sex- and age-associated factors drive the pathophysiology of MASLDSemantic proximity Read