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Article

Neuropeptide VGF Promotes Maturation of Hippocampal Dendrites That Is Reduced by Single Nucleotide Polymorphisms.

International journal of molecular sciences - 11 Mar 2017

Behnke Joseph, Cheedalla Aneesha, Bhatt Vatsal, Bhat Maysa, Teng Shavonne, Palmieri Alicia, Windon Charles Christian, Thakker-Varia Smita, Alder Janet

Abstract excerpt

The neuropeptide VGF (non-acronymic) is induced by brain-derived neurotrophic factor and promotes hippocampal neurogenesis, as well as synaptic activity. However, morphological changes induced by VGF have not been elucidated. Developing hippocampal neurons were exposed to VGF through bath application or virus-mediated expression in vitro. VGF-derived peptide, TLQP-62, enhanced dendritic branching, and outgrowth....

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Source

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Identifiers

PMID: 28287464
DOI: 10.3390/ijms18030612
PMCID: PMC5372628

Genes

VGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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