Article
Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p.
Molecular and cellular biology - 1 Jul 2002
Kabani Mehdi, Beckerich Jean-Marie, Brodsky Jeffrey L
Abstract excerpt
We report on the identification of Fes1p (yBR101cp) as a cytosolic homologue of Sls1p, an endoplasmic reticulum (ER) protein previously shown to act as a nucleotide exchange factor for yeast BiP (M. Kabani, J.-M. Beckerich, and C. Gaillardin, Mol. Cell. Biol. 20:6923-6934, 2000). We found that Fes1p associates preferentially to the ADP-bound form of the cytosolic Hsp70 molecular chaperone Ssa1p and promotes...
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