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Article

Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites.

BMC genomics - 8 Aug 2014

Wu Di, Yang Gang, Zhang Lifang, Xue Jiwei, Wen Zhining, Li Menglong

Abstract excerpt

BACKGROUND: Emerging studies demonstrate that single nucleotide polymorphisms (SNPs) resided in the microRNA recognition element seed sites (MRESSs) in 3'UTR of mRNAs are putative biomarkers for human diseases and cancers. However, exhaustively experimental validation for the causality of MRESS SNPs is impractical. Therefore bioinformatics have been introduced to predict causal MRESS SNPs. Genome-wide association...

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PMID: 25106527
DOI: 10.1186/1471-2164-15-669
PMCID: PMC4246476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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