Article
Alzheimer's disease risk SNPs show no strong effect on miRNA expression in human lymphoblastoid cell lines.
Neurobiology of aging - 1 Feb 2020
Wohlers Inken, Schulz Colin, Kilpert Fabian, Bertram Lars
Abstract excerpt
The role of microRNAs (miRNAs) in the pathogenesis of Alzheimer's disease (AD) is currently extensively investigated. In this study, we assessed the potential impact of AD genetic risk variants on miRNA expression by performing large-scale bioinformatic data integration. Our analysis was based on genetic variants from 3 AD genome-wide association studies (GWASs). Association with miRNA expression was tested by...
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